NAME¶
Bio::Map::GenePosition - A typed position, suitable for modelling the various
regions of a gene.
SYNOPSIS¶
use Bio::Map::GenePosition;
use Bio::Map::GeneMap;
# say that the first transcript of a particular gene on a particular map
# (species) is 1000bp long
my $map = Bio::Map:GeneMap->get(-universal_name => 'BRCA2',
-species => 'human');
my $gene = $map->gene;
Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 0,
-length => 1000,
-type => 'transcript');
# say that the coding region of the gene starts 30bp into the first
# transcript
Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 30,
-length => 600,
-type => 'coding');
# A GenePosition isa PositionWithSequence, so can have sequence associated
# with it
my $exon = Bio::Map::GenePosition->new(-map => $map,
-element => $gene,
-start => 0,
-type => 'exon',
-seq => 'ATGGGGTGGG');
my $length = $exon->length; # $length is 10
DESCRIPTION¶
Define where various sub-regions (transcripts, exons, introns etc.) of a gene
are. Do this so that you can then go onto to model other mappable elements as
having positions 20bp upstream of transcript 2, or 10bp into intron 3 etc.,
all without having to know the absolute position of anything.
See Bio::Map::GeneRelative and t/Map/Map.t for more example usage.
FEEDBACK¶
Mailing Lists¶
User feedback is an integral part of the evolution of this and other Bioperl
modules. Send your comments and suggestions preferably to the Bioperl mailing
list. Your participation is much appreciated.
bioperl-l@bioperl.org - General discussion
http://bioperl.org/wiki/Mailing_lists - About the mailing lists
Support¶
Please direct usage questions or support issues to the mailing list:
bioperl-l@bioperl.org
rather than to the module maintainer directly. Many experienced and reponsive
experts will be able look at the problem and quickly address it. Please
include a thorough description of the problem with code and data examples if
at all possible.
Reporting Bugs¶
Report bugs to the Bioperl bug tracking system to help us keep track of the bugs
and their resolution. Bug reports can be submitted via the web:
https://github.com/bioperl/bioperl-live/issues
AUTHOR - Sendu Bala¶
Email bix@sendu.me.uk
APPENDIX¶
The rest of the documentation details each of the object methods. Internal
methods are usually preceded with a _
new¶
Title : new
Usage : my $obj = Bio::Map::GenePosition->new();
Function: Builds a new Bio::Map::GenePosition object
Returns : Bio::Map::GenePosition
Args : -map => Bio::Map::GeneMap object
-element => Bio::Map::Gene object
-relative => Bio::Map::GeneRelative object
-type => 'transcript|coding|exon|intron', REQUIRED
-seq => string, length of this string will set the length
of this position's range
* If this position has no range, or if a single value can describe
the range *
-value => scalar : something that describes the single
point position or range of this
Position, most likely an int
* Or if this position has a range, at least two of *
-start => int : value of the start co-ordinate
-end => int : value of the end co-ordinate
-length => int : length of the range
map¶
Title : map
Usage : my $map = $position->map();
$position->map($map);
Function: Get/set the map the position is in.
Returns : L<Bio::Map::MapI>
Args : none to get
new L<Bio::Map::MapI> to set
element¶
Title : element
Usage : my $element = $position->element();
$position->element($element);
Function: Get/set the element the position is for.
Returns : L<Bio::Map::MappableI>
Args : none to get
new L<Bio::Map::MappableI> to set
type¶
Title : type
Usage : my $type = $position->type();
$position->type($type);
Function: Get/set the type of this position.
Returns : string
Args : none to get, OR
string transcript|coding|exon|intron to set
relative¶
Title : relative
Usage : my $relative = $position->relative();
$position->relative($relative);
Function: Get/set the thing this Position's coordinates (numerical(), start(),
end()) are relative to, as described by a RelativeI object.
Returns : Bio::Map::GeneRelative. The default GeneRelative returned has a
meaning that depends on the type() of GenePosition this is:
'transcript' : "relative to the start of the gene on the
Position's map"
'coding|exon|intron' : "relative to the start of the default
transcript of the gene on the Position's map"
Args : none to get, OR
Bio::Map::GeneRelative to set
seq¶
Title : seq
Usage : my $string = $position->seq();
Function: Get/set the sequence as a string of letters. If no sequence is
manually set by you, the position's map will be asked for the
sequence, and if available, that will be returned.
Returns : scalar
Args : Optionally on set the new value (a string). An optional second
argument presets the alphabet (otherwise it will be guessed).