.\" DO NOT MODIFY THIS FILE! It was generated by help2man 1.40.4. .TH VCF-ISEC "1" "July 2011" "vcf-isec 0.1.5" "User Commands" .SH NAME vcf-isec \- create intersections, unions, complements on bgzipped and tabix indexed VCF or tab-delimited files .SH SYNOPSIS .B vcf-isec [\fIOPTIONS\fR] \fIfile1.vcf file2.vcf \fR... .SH DESCRIPTION About: Create intersections, unions, complements on bgzipped and tabix indexed VCF or tab\-delimited files. .IP Note that lines from all files can be intermixed together on the output, which can yield unexpected results. .SH OPTIONS .TP \fB\-C\fR, \fB\-\-chromosomes\fR Process the given chromosomes (comma\-separated list or one chromosome per line in a file). .TP \fB\-c\fR, \fB\-\-complement\fR Output positions present in the first file but missing from the other files. .TP \fB\-d\fR, \fB\-\-debug\fR Debugging information .TP \fB\-f\fR, \fB\-\-force\fR Continue even if the script complains about differing columns. .TP \fB\-o\fR, \fB\-\-one\-file\-only\fR Print only entries from the left\-most file. Without \fB\-o\fR, all unique positions will be printed. .TP \fB\-n\fR, \fB\-\-nfiles\fR [+\-=] Output positions present in this many (=), this many or more (+), or this many or fewer (\-) files. .TP \fB\-p\fR, \fB\-\-prefix\fR If present, multiple files will be created with all possible isec combinations. (Suitable for Venn Diagram analysis.) .TP \fB\-t\fR, \fB\-\-tab\fR Tab\-delimited file with indexes of chromosome and position columns. (1\-based indexes) .TP \fB\-w\fR, \fB\-\-win\fR In repetitive sequences, the same indel can be called at different positions. Consider records this far apart as matching (be it a SNP or an indel). .TP \fB\-h\fR, \-?, \fB\-\-help\fR This help message. .SH EXAMPLES .IP bgzip file.vcf; tabix \fB\-p\fR vcf file.vcf.gz bgzip file.tab; tabix \fB\-s\fR 1 \fB\-b\fR 2 \fB\-e\fR 2 file.tab.gz