.\" (C) Copyright 2015 Afif Elghraoui , .TH SIMPLE "1" "May 2015" "simple 0~20150520+2004" "User Commands" .SH NAME simple \- the obvious array-based kmer counter .SH SYNOPSIS .B simple .RB [ \-f | \-r | \-C ] .RB [ \-c .IR compression ] .RB [ \-m .IR mersize ] .BI \-i \0input .BI \-o \0output .SH DESCRIPTION .B simple is a very simple mer counter. It allocates a gigantic 32-bit array, populates the array with mers, sorts, and writes the output. It will allocate 4 bytes per kmer. k=16 will require 16 GB to run. .SH OPTIONS .TP .BI \-i \0input .TP .BI \-o \0output .TP .BI \-m \0mersize the mer size. Default is 22 .TP .B \-f forward kmer (this is the default) .TP .B \-r reverse kmer .TP .B \-C canonical kmer (lexicographically smaller of the forward and reverse kmer at each location) .TP .BI \-c \0# mer compression .SH SEE ALSO .BR meryl (1)