.\" DO NOT MODIFY THIS FILE! It was generated by help2man 1.47.15. .TH COOLER "1" "June 2020" "cooler 0.8.7" "User Commands" .SH NAME cooler \- sparse, compressed, binary persistent storage .SH SYNOPSIS .B cooler [\fI\,OPTIONS\/\fR] \fI\,COMMAND \/\fR[\fI\,ARGS\/\fR]... .SH DESCRIPTION Cooler is a support library for a sparse, compressed, binary persistent storage format, also called cooler, used to store genomic interaction data, such as Hi-C contact matrices. .P The cooler file format is an implementation of a genomic matrix data model using HDF5 as the container format. The cooler package includes a suite of command line tools and a Python API to facilitate creating, querying and manipulating cooler files. .SH OPTIONS .TP \fB\-v\fR, \fB\-\-verbose\fR Verbose logging. .TP \fB\-d\fR, \fB\-\-debug\fR On error, drop into the post\-mortem debugger shell. .TP \fB\-V\fR, \fB\-\-version\fR Show the version and exit. .TP \fB\-h\fR, \fB\-\-help\fR Show this message and exit. .SS "Commands:" .TP cload Create a cooler from genomic pairs and bins. .TP load Create a cooler from a pre\-binned matrix. .TP merge Merge multiple coolers with identical axes. .TP coarsen Coarsen a cooler to a lower resolution. .TP zoomify Generate a multi\-resolution cooler file by coarsening. .TP balance Out\-of\-core matrix balancing. .TP info Display a cooler's info and metadata. .TP dump Dump a cooler's data to a text stream. .TP show Display and browse a cooler in matplotlib. .TP makebins Generate fixed\-width genomic bins. .TP digest Generate fragment\-delimited genomic bins. .TP csort Sort and index a contact list. .TP ls List all coolers inside a file. .TP cp Copy a cooler from one file to another or within the same file. .TP ln Create a hard link to a cooler (rather than a true copy) in the... .TP mv Rename a cooler within the same file. .TP tree Display a file's data hierarchy. .TP attrs Display a file's attribute hierarchy. .SH AUTHOR This manpage was written by Andreas Tille for the Debian distribution and can be used for any other usage of the program.