.\" DO NOT MODIFY THIS FILE!  It was generated by help2man 1.47.6.
.TH BOWTIE2-BUILD "1" "September 2018" "bowtie2-build 2.3.4.3" "User Commands"
.SH NAME
bowtie2-build \- wrapper for bowtie2-build-*
.SH SYNOPSIS
.B bowtie2-build
[\fI\,options\/\fR]\fI\,* <reference_in> <bt2_index_base>\/\fR
.SH DESCRIPTION
.TP
Bowtie 2 version 2.3.4.3 by Ben Langmead (langmea@cs.jhu.edu, www.cs.jhu.edu/~langmea)
.TP
reference_in
comma\-separated list of files with ref sequences
.TP
bt2_index_base
write bt2 data to files with this dir/basename
.PP
*** Bowtie 2 indexes work only with v2 (not v1).  Likewise for v1 indexes. ***
.SH OPTIONS
\fB\-f\fR
reference files are Fasta (default)
.TP
\fB\-c\fR
reference sequences given on cmd line (as
<reference_in>)
.TP
\fB\-\-large\-index\fR
force generated index to be 'large', even if ref
has fewer than 4 billion nucleotides
.TP
\fB\-\-debug\fR
use the debug binary; slower, assertions enabled
.TP
\fB\-\-sanitized\fR
use sanitized binary; slower, uses ASan and/or UBSan
.TP
\fB\-\-verbose\fR
log the issued command
.TP
\fB\-a\fR/\-\-noauto
disable automatic \fB\-p\fR/\-\-bmax/\-\-dcv memory\-fitting
.TP
\fB\-p\fR/\-\-packed
use packed strings internally; slower, less memory
.TP
\fB\-\-bmax\fR <int>
max bucket sz for blockwise suffix\-array builder
.TP
\fB\-\-bmaxdivn\fR <int>
max bucket sz as divisor of ref len (default: 4)
.TP
\fB\-\-dcv\fR <int>
diff\-cover period for blockwise (default: 1024)
.TP
\fB\-\-nodc\fR
disable diff\-cover (algorithm becomes quadratic)
.TP
\fB\-r\fR/\-\-noref
don't build .3/.4 index files
.TP
\fB\-3\fR/\-\-justref
just build .3/.4 index files
.TP
\fB\-o\fR/\-\-offrate <int>
SA is sampled every 2^<int> BWT chars (default: 5)
.TP
\fB\-t\fR/\-\-ftabchars <int>
# of chars consumed in initial lookup (default: 10)
.TP
\fB\-\-threads\fR <int>
# of threads
.TP
\fB\-\-seed\fR <int>
seed for random number generator
.TP
\fB\-q\fR/\-\-quiet
verbose output (for debugging)
.TP
\fB\-h\fR/\-\-help
print detailed description of tool and its options
.TP
\fB\-\-usage\fR
print this usage message
.TP
\fB\-\-version\fR
print version information and quit