.TH "hmmpress" 1 "Nov 2020" "HMMER 3.3.2" "HMMER Manual" .SH NAME hmmpress \- prepare a profile database for hmmscan .SH SYNOPSIS .B hmmpress [\fIoptions\fR] .I hmmfile .SH DESCRIPTION .PP Constructs binary compressed datafiles for .BR hmmscan , starting from a profile database .I hmmfile in standard HMMER3 format. The .B hmmpress step is required for .B hmmscan to work. .PP Four files are created: .IB hmmfile .h3m, .IB hmmfile .h3i, .IB hmmfile .h3f, and .IB hmmfile .h3p. The .IB hmmfile .h3m file contains the profile HMMs and their annotation in a binary format. The .IB hmmfile .h3i file is an SSI index for the .IB hmmfile .h3m file. The .IB hmmfile .h3f file contains precomputed data structures for the fast heuristic filter (the MSV filter). The .IB hmmfile .h3p file contains precomputed data structures for the rest of each profile. .PP .I hmmfile may not be '\-' (dash); running .B hmmpress on a standard input stream rather than a file is not allowed. .SH OPTIONS .TP .B \-h Help; print a brief reminder of command line usage and all available options. .TP .B \-f Force; overwrites any previous hmmpress'ed datafiles. The default is to bitch about any existing files and ask you to delete them first. .SH SEE ALSO See .BR hmmer (1) for a master man page with a list of all the individual man pages for programs in the HMMER package. .PP For complete documentation, see the user guide that came with your HMMER distribution (Userguide.pdf); or see the HMMER web page (http://hmmer.org/). .SH COPYRIGHT .nf Copyright (C) 2020 Howard Hughes Medical Institute. Freely distributed under the BSD open source license. .fi For additional information on copyright and licensing, see the file called COPYRIGHT in your HMMER source distribution, or see the HMMER web page (http://hmmer.org/). .SH AUTHOR .nf http://eddylab.org .fi