'\" t .\" Title: LIBSCAN .\" Author: Debian Med Packaging Team .\" Generator: DocBook XSL Stylesheets v1.75.2 .\" Date: 08/11/2010 .\" Manual: EMBOSS Manual for Debian .\" Source: DOMAINATRIX 0.1.0+20100721 .\" Language: English .\" .TH "LIBSCAN" "1e" "08/11/2010" "DOMAINATRIX 0.1.0+20100721" "EMBOSS Manual for Debian" .\" ----------------------------------------------------------------- .\" * Define some portability stuff .\" ----------------------------------------------------------------- .\" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ .\" http://bugs.debian.org/507673 .\" http://lists.gnu.org/archive/html/groff/2009-02/msg00013.html .\" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ .ie \n(.g .ds Aq \(aq .el .ds Aq ' .\" ----------------------------------------------------------------- .\" * set default formatting .\" ----------------------------------------------------------------- .\" disable hyphenation .nh .\" disable justification (adjust text to left margin only) .ad l .\" ----------------------------------------------------------------- .\" * MAIN CONTENT STARTS HERE * .\" ----------------------------------------------------------------- .SH "NAME" libscan \- Diagnostic searches for protein families\&. .SH "SYNOPSIS" .HP \w'\fBlibscan\fR\ 'u \fBlibscan\fR \fB\-mode\ \fR\fB\fIlist\fR\fR \fB\-grib\ \fR\fB\fIboolean\fR\fR \fB\-henik\ \fR\fB\fIboolean\fR\fR \fB\-hmm\ \fR\fB\fIboolean\fR\fR \fB\-sam\ \fR\fB\fIboolean\fR\fR \fB\-pssm\ \fR\fB\fIboolean\fR\fR \fB\-sig\ \fR\fB\fIboolean\fR\fR \fB\-hmmpath\ \fR\fB\fIstring\fR\fR \fB\-hmmextn\ \fR\fB\fIstring\fR\fR \fB\-hmmoutpath\ \fR\fB\fIstring\fR\fR \fB\-hmmoutextn\ \fR\fB\fIstring\fR\fR \fB\-sampath\ \fR\fB\fIstring\fR\fR \fB\-samextn\ \fR\fB\fIstring\fR\fR \fB\-samoutpath\ \fR\fB\fIstring\fR\fR \fB\-samoutextn\ \fR\fB\fIstring\fR\fR \fB\-pssmpath\ \fR\fB\fIstring\fR\fR \fB\-pssmextn\ \fR\fB\fIstring\fR\fR \fB\-niter\ \fR\fB\fIinteger\fR\fR \fB\-thresh\ \fR\fB\fIfloat\fR\fR \fB\-maxhit\ \fR\fB\fIinteger\fR\fR \fB\-pssmoutpath\ \fR\fB\fIstring\fR\fR \fB\-pssmoutextn\ \fR\fB\fIstring\fR\fR \fB\-gbvpath\ \fR\fB\fIstring\fR\fR \fB\-gbvextn\ \fR\fB\fIstring\fR\fR \fB\-gbvgapo\ \fR\fB\fIfloat\fR\fR \fB\-gbvgape\ \fR\fB\fIfloat\fR\fR \fB\-gbvoutpath\ \fR\fB\fIstring\fR\fR \fB\-gbvoutextn\ \fR\fB\fIstring\fR\fR \fB\-hnfpath\ \fR\fB\fIstring\fR\fR \fB\-hnfextn\ \fR\fB\fIstring\fR\fR \fB\-hnfgapo\ \fR\fB\fIfloat\fR\fR \fB\-hnfgape\ \fR\fB\fIfloat\fR\fR \fB\-hnfoutpath\ \fR\fB\fIstring\fR\fR \fB\-hnfoutextn\ \fR\fB\fIstring\fR\fR \fB\-sigpath\ \fR\fB\fIstring\fR\fR \fB\-sigextn\ \fR\fB\fIstring\fR\fR \fB\-nterm\ \fR\fB\fIlist\fR\fR \fB\-sub\ \fR\fB\fImatrixf\fR\fR \fB\-siggapo\ \fR\fB\fIfloat\fR\fR \fB\-siggape\ \fR\fB\fIfloat\fR\fR \fB\-sigoutpath\ \fR\fB\fIstring\fR\fR \fB\-sigoutextn\ \fR\fB\fIstring\fR\fR \fB\-db\ \fR\fB\fIseqset\fR\fR \fB\-scopf\ \fR\fB\fIinfile\fR\fR .HP \w'\fBlibscan\fR\ 'u \fBlibscan\fR \fB\-help\fR .SH "DESCRIPTION" .PP \fBlibscan\fR is a command line program from EMBOSS (\(lqthe European Molecular Biology Open Software Suite\(rq)\&. It is part of the "Protein:3D Structure" command group(s)\&. .SH "OPTIONS" .PP \fB\-mode\fR \fIlist\fR .RS 4 libscan runs in one of two modes either (i) database search mode or (ii) library screen mode\&. In database search mode libscan reads one or more directories each containing a single type of discriminating element, the permitted types are sparse sequence signature, Gribskov profile, Henikoff profile or hidden Markov model\&. In library screen mode, libscan reads a sequence set, screens each sequence against the library (directories of discriminating elements) and writes a library scan file (of top\-scoring families) for each one\&. Default value: 2 .RE .PP \fB\-grib\fR \fIboolean\fR .RS 4 Default value: N .RE .PP \fB\-henik\fR \fIboolean\fR .RS 4 Default value: N .RE .PP \fB\-hmm\fR \fIboolean\fR .RS 4 Default value: N .RE .PP \fB\-sam\fR \fIboolean\fR .RS 4 Default value: N .RE .PP \fB\-pssm\fR \fIboolean\fR .RS 4 Default value: Y .RE .PP \fB\-sig\fR \fIboolean\fR .RS 4 Default value: N .RE .PP \fB\-hmmpath\fR \fIstring\fR .RS 4 Default value: \&./lib/ .RE .PP \fB\-hmmextn\fR \fIstring\fR .RS 4 Default value: \&.hmm .RE .PP \fB\-hmmoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-hmmoutextn\fR \fIstring\fR .RS 4 Default value: \&.hmmout .RE .PP \fB\-sampath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-samextn\fR \fIstring\fR .RS 4 Default value: \&.mod .RE .PP \fB\-samoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-samoutextn\fR \fIstring\fR .RS 4 Default value: \&.samout .RE .PP \fB\-pssmpath\fR \fIstring\fR .RS 4 Default value: /data/structure/lib/pssm/ .RE .PP \fB\-pssmextn\fR \fIstring\fR .RS 4 Default value: \&.chk .RE .PP \fB\-niter\fR \fIinteger\fR .RS 4 Default value: 1 .RE .PP \fB\-thresh\fR \fIfloat\fR .RS 4 Default value: 100 .RE .PP \fB\-maxhit\fR \fIinteger\fR .RS 4 Default value: 1000 .RE .PP \fB\-pssmoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-pssmoutextn\fR \fIstring\fR .RS 4 Default value: \&.pssmout .RE .PP \fB\-gbvpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-gbvextn\fR \fIstring\fR .RS 4 Default value: \&.grib .RE .PP \fB\-gbvgapo\fR \fIfloat\fR .RS 4 Default value: 10\&.0 .RE .PP \fB\-gbvgape\fR \fIfloat\fR .RS 4 Default value: 0\&.5 .RE .PP \fB\-gbvoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-gbvoutextn\fR \fIstring\fR .RS 4 Default value: \&.gribout .RE .PP \fB\-hnfpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-hnfextn\fR \fIstring\fR .RS 4 Default value: \&.henik .RE .PP \fB\-hnfgapo\fR \fIfloat\fR .RS 4 Default value: 10\&.0 .RE .PP \fB\-hnfgape\fR \fIfloat\fR .RS 4 Default value: 0\&.5 .RE .PP \fB\-hnfoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-hnfoutextn\fR \fIstring\fR .RS 4 Default value: \&.henikout .RE .PP \fB\-sigpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-sigextn\fR \fIstring\fR .RS 4 Default value: \&.sig .RE .PP \fB\-nterm\fR \fIlist\fR .RS 4 Default value: 1 .RE .PP \fB\-sub\fR \fImatrixf\fR .RS 4 Default value: EBLOSUM62 .RE .PP \fB\-siggapo\fR \fIfloat\fR .RS 4 Default value: 10\&.0 .RE .PP \fB\-siggape\fR \fIfloat\fR .RS 4 Default value: 0\&.5 .RE .PP \fB\-sigoutpath\fR \fIstring\fR .RS 4 Default value: \&./ .RE .PP \fB\-sigoutextn\fR \fIstring\fR .RS 4 Default value: \&.sigout .RE .PP \fB\-db\fR \fIseqset\fR .RS 4 In database search mode libscan scans each discriminating element against a sequence set\&. In library screen mode, libscan reads a sequence set and screens each sequence against the library (directories of disciminating elements) Default value: 49142\&.vdhf .RE .PP \fB\-scopf\fR \fIinfile\fR .RS 4 In either mode, a \*(Aqscop classification file\*(Aq is required as a source of family classification data\&. A scop classification file contains classification and other data for domains from the scop database\&. The file is in embl\-like format and is generated by scopparse\&. Domain sequence information can be added to the file by using scopseqs\&. Default value: /data/structure/dcf/scop_raw\&.dcf .RE .SH "BUGS" .PP Bugs can be reported to the Debian Bug Tracking system (http://bugs\&.debian\&.org/emboss), or directly to the EMBOSS developers (http://sourceforge\&.net/tracker/?group_id=93650&atid=605031)\&. .SH "SEE ALSO" .PP libscan is fully documented via the \fBtfm\fR(1) system\&. .SH "AUTHOR" .PP \fBDebian Med Packaging Team\fR <\&debian\-med\-packaging@lists\&.alioth\&.debian\&.org\&> .RS 4 Wrote the script used to autogenerate this manual page\&. .RE .SH "COPYRIGHT" .br .PP This manual page was autogenerated from an Ajax Control Definition of the EMBOSS package\&. It can be redistributed under the same terms as EMBOSS itself\&. .sp